Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay
نویسندگان
چکیده
منابع مشابه
Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay
The NF-κB transcription factor family plays a central role in innate immunity and inflammation processes and is frequently dysregulated in cancer. We developed an NF-κB functional assay in yeast to investigate the following issues: transactivation specificity of NF-κB proteins acting as homodimers or heterodimers; correlation between transactivation capacity and in vitro DNA binding measurement...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0130170